Automation control and optimization technology of fermentation process, it is not only concerning fungus whether can play the maximum production capacity and improve work efficiency, but also effect next processing difficult degree. It is a connecting link between the preceding and the following in the whole fermentation process, which also raise an important branch of fermentation engineering technology. Because the feature of fermentation process is obvious, such as a kinetic model is non-linear and as high as variable, hard to measure important state variable and slow response rate, the traditional process control and optimization methods are hard to adapt the special requirements of fermentation process optimized control. Develop and establish which match with fermentation process and be provided with characteristics of parse, control of fermentation process and optimization technology, it has a good significance for promotion the overall level of industrial technology, biotechnology industry and realize scientific industrialization.